Generic name: Guaifenesin(gwye-fen´e-sin)
Brand name:Amonidrin, Anti-Tuss, Breonesin, Gee-Gee, GG-Cen, Glyceryl
Guaiacolate, Glycotuss, Glytuss, Guaituss, Hytuss, Malotuss,
Classifications: antitussive; expectorant
100 mg/5 mL syrup; 100 mg/5 mL, 200 mg/5 mL liquid; 200 mg cap
Enhances reflex outflow of respiratory tract fluids by irritation of gastric mucosa.
Aids in expectoration by reducing adhesiveness and surface tension of secretions.
To combat dry, nonproductive cough associated with colds and bronchitis. A common ingredient in cough mixtures.
Hypersensitivity to guaifenesin; pregnancy (category C), lactation.
Route & Dosage
adult: PO 200–400 mg q4h up to 2.4 g/d
child: PO <2 y: 12 mg/kg/d in 6 divided doses; 2–5 y: 50–100 mg q4h up to 600 mg/d; 6–11 y, 100–200 mg q4h up to 1.2 g/d
- Ensure that sustained release form of drug is not chewed or crushed. It must be swallowed whole.
- Follow dose with a full glass of water if not contraindicated.
- Carefully observe maximum daily doses for adults and children
GI: Low incidence of nausea.
Assessment & Drug Effects
- Monitor for therapeutic effectiveness. Persistent cough may indicate a serious condition requiring further diagnostic work.
- Notify physician if high fever, rash, or headaches develop.
Patient & Family Education
- Increase fluid intake to help loosen mucus; drink at least 8 glasses of fluid daily
- Contact physician if cough persists beyond 1 wk.
- Contact physician if high fever, rash, or headache develops
- Do not breast feed while taking this drug.