are commonly used by lay people to treat conditions and infections without consultation with doctors. One very common broad-spectrum antibiotic that is cheap and almost all people know is Amoxicillin.

Generic Name: Amoxicillin

Brand Name: Amoxil, Polymox

Classification: Non-narcotic analgesic, Antipyretic,Antibiotic


  1. Ear, nose, and throat infections due to Streptococcus species.
  2. GU Infections due to Escherichia coli, Proteus miribalis, Enterococcus facecalis.
  3. Skin infections due to Streptococcus, S. pneumonia, Staphylococcus, or H. haemophilus
  4. Acute uncomplicated gonococcal infections due to Neisseria gonorrhoeae.
  5. In combination with omeprazole or lansoprazole to treat duodenal ulcers by eradicating Helicobacter pylori.


This drug is a semi-synthetic broad spectrum penicillin closely related to Ampicillin. It binds to Penicillin-binding proteins in the cytoplasmic membranes of bacteria, thus inhibiting cell-wall synthesis. It also inhibits cell growth and cell division. It is better absorbed than Ampicillin.


  1. Hypersensitivity
  2. Use of the 875mg tablet in clients with a GFR less than 30mL/minute.

Special Concerns:

  1. Safe use during pregnancy has not been established.
  2. Drug may decrease effectiveness of oral contraceptives.


  1. Hypersensitivity
  2. Nausea
  3. Vomiting
  4. Gastritis
  5. Stomatitis


Per Orem: usual dose of 500mg q8h or 500mg q12h. For gonococcal infections: 3 grams single dose.

Nursing Considerations:

  1. Note for any hypersensitivity reaction
  2. Instruct clients that therapeutic regimen must be completed even if symptoms subside.
  3. Child’s dose should not exceed maximum adult dose.
  4. Clients with GFR of 10-30 mL/min should receive 250-500mg q12h.
  5. Monitor CBC, renal and liver function tests.
  6. May be taken with food.
  7. Antibiotic resistance may occur if used without practitioner consultation as duration of therapy may not be completed.
  8. Report: bleeding, sore throat, rash, diarrhea, worsening of symptoms, lack of response.


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